For CKD, Id separate the proven support from the experimental but interesting category., Astragalus root extract is probably the most tried and true natural compound Id look at first. Theres Selenium supplementation in chronic kidney disease patients undergoing haemodialysis: a systematic review of the effects on plasma selenium, antioxidant and inflammatory markers, immunological parameters and thyroid hormones Nutrition Research Reviews Glutathione specific gammaglutamylcyclotransferase 1 (CHAC1) increases kidney disease risk by modulating ferroptosis Science Translational Medicine Journal of Cellular Biochemistry Wiley Online Library