Blister Cell in G6PD Deficiency , Red Blood Cell with a clear vacuole like area on its membrane, resembling a blister., It usually results when splenic macrophages remove precipitated Heinz File:Glutathion metabolism DE state in G6PD deficiency.png Wikimedia Commons Figure 2 from Impact of glucose 6 phosphate dehydrogenase deficiency on the pathophysiology of cardiovascular disease. Semantic Scholar HMP Pathway Simplified: NADPH Role & G6PD Deficiency Explained